
Sku: WP7100

Catalog No.: WP10259
Specification: 50μL/100μL
Stock: In stock
U-Blot® GRK2 (Phospho Tyr86) Polyclonal Antibody Learn more
Background:The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],
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