U-Blot® TNF-R2 Polyclonal Antibody

Name: U-Blot® TNF-R2 Polyclonal Antibody
SKU: WP14811
Availability: InStock

$268.00

Size:50μL

SKU: WP14811-50

Catalog No.: WP14811

Specification: 50μL/100μL

Stock: In stock

U-Blot® TNF-R2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP14811
SKU: WP14811-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: TNF-R2
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 48kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human TNF Receptor II. AA range:376-425
Sequence: --
Specificity: TNF-R2 Polyclonal Antibody detects endogenous levels of TNF-R2 protein.
Gene Name: TNFRSF1B
Protein Name: Tumor necrosis factor receptor superfamily member 1B
Other Name: TNFRSF1B;TNFBR;TNFR2;Tumor necrosis factor receptor superfamily member 1B;Tumor necrosis factor receptor 2;TNF-R2;Tumor necrosis factor receptor type II;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD antigen CD120b;Etanercept
Organism-1: Human
Gene ID-1: 7133
SwissProt-1: P20333
Organism-2: Mouse
Gene ID-2: 21938
SwissProt-2: P25119
Organism-3: Rat
Gene ID-3: 156767
SwissProt-3: Q80WY6
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Tumor necrosis factor-binding protein 2]: Secreted.