Recombinant Human/Mouse/Rat TGFB3 Protein

Recombinant Human/Mouse/Rat TGFB3 Protein
Recombinant Human/Mouse/Rat TGFB3 Protein
$210.00
Size:10μg
SKU: PR00192-10μg

Catalog No.: PR00192

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

1
Share:fx@link

Product information

Product detailsSpecificationsQ & AEducation

Background:Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate.

Product Overview

Catalog No.
PR00192
SKU
PR00192-10μg
Category
TGF-beta Superfamily
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
TGFB3
Background
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3,mammals develop a deformity known as a cleft palate.
Species
Human/Mouse/Rat
Source
HEK293 Cells
Tags
Tag free
Accession
P10600
KnownAs
Transforming growth factor beta-3; TGFB3; TGF-beta-3; Latency-associated peptide; LAP
Protein Length
Ala301-Ser412(Tyr340Phe)
Predicted Molecular Mass
12.7 KDa
N-terminal Sequence
--
SDS-PAGE
12-14 KDa, reducing conditions
Endotoxin
<0.01 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl，150mM NaCl，4%Mannitol，pH 2.5.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Request Technical Support
Keywords:TGF-beta Superfamily