Recombinant Mouse GZMB Protein, C-His

Recombinant Mouse GZMB Protein, C-His
Recombinant Mouse GZMB Protein, C-His
$210.00
Size:10μg
SKU: PR00301-10μg

Catalog No.: PR00301

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Product Overview

Catalog No.
PR00301
SKU
PR00301-10μg
Category
Others Family
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
GZMB
Background
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Species
Mouse
Source
HEK293 Cells
Tags
C-6His
Accession
P04187
KnownAs
Granzyme B(G;H);CTLA-1;Cytotoxic cell protease 1;CCP1;Fragmentin-2;Gzmb;Ctla-1; Ctla1
Protein Length
Gly19-Ser247
Predicted Molecular Mass
26.5 KDa
N-terminal Sequence
--
SDS-PAGE
35 KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Liquid
Formulation
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
--

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Others Family