Recombinant Human PRCP Protein, C-His

Recombinant Human PRCP Protein, C-His
Recombinant Human PRCP Protein, C-His
$210.00
Size:10μg
SKU: PR02152-10μg

Catalog No.: PR02152

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.

Product Overview

Catalog No.
PR02152
SKU
PR02152-10μg
Category
Others Family
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
PRCP
Background
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Species
Human
Source
HEK293 Cells
Tags
C-6His
Accession
P42785
KnownAs
Lysosomal Pro-X Carboxypeptidase; Angiotensinase C; Lysosomal Carboxypeptidase C; Proline Carboxypeptidase; Prolylcarboxypeptidase; PRCP; PRCP; PCP
Protein Length
Leu22-His496
Predicted Molecular Mass
54.5 KDa
N-terminal Sequence
--
SDS-PAGE
60-90 KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by reducing SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Liquid
Formulation
Supplied as a 0.2 μm filtered solution of 20mM NaAc-HAc, 150mM NaCl, 10% Glycerol, pH4.5.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
--

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Others Family