Recombinant Human NOTCH1 Protein, N-His

Recombinant Human NOTCH1 Protein, N-His
Recombinant Human NOTCH1 Protein, N-His
$290.00
Size:50μg
SKU: PR15561-50μg

Catalog No.: PR15561

Specification: 50ug/100ug/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

1
Share:fx@link

Product information

Product detailsSpecificationsQ & AEducation

Background:Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531 amino acid (aa) precursor that contains an 18 aa signal sequence, a 1707 aa extracellular domain (ECD) with 36 EGFlike repeats and three Lin12/notch repeats, a 21 aa transmembrane segment and a 785 aa cytoplasmic domain that contains six ankyrin repeats, a glutamine-rich domain and a PEST sequence. Notch1 may play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation and may be involved in mesoderm development, somite formation and neurogenesis.

Product Overview

Catalog No.
PR15561
SKU
PR15561-50μg
Category
Others Family
Product Type
Other
Size
50ug/100ug/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
NOTCH1
Background
Mouse Notch1 is a 300 kDa type I transmembrane glycoprotein and it functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Mouse Notch1 is synthesized as a 2531 amino acid (aa) precursor that contains an 18 aa signal sequence, a 1707 aa extracellular domain (ECD) with 36 EGFlike repeats and three Lin12/notch repeats, a 21 aa transmembrane segment and a 785 aa cytoplasmic domain that contains six ankyrin repeats, a glutamine-rich domain and a PEST sequence. Notch1 may play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation and may be involved in mesoderm development, somite formation and neurogenesis.
Species
Human
Source
E. coli
Tags
N-His
Accession
P46531
KnownAs
NEXT, NICD, NOTCH1, Neurogenic locus notch homolog protein 1, Notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, TAN1, Translocation-associated notch protein TAN-1, hN1
Protein Length
Lys1759-Ala2127
Predicted Molecular Mass
43.10 kDa
N-terminal Sequence
--
SDS-PAGE
--
Endotoxin
--
Concentration
--
Purity-SDS-PAGE
>90% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of 0.5-1 mg/mL.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Request Technical Support
Keywords:Others Family