Recombinant Canine CD274/PD-L1/B7-H1 protein, C-His

Recombinant Canine CD274/PD-L1/B7-H1 protein, C-His
Recombinant Canine CD274/PD-L1/B7-H1 protein, C-His
$290.00
Size:20μg
SKU: PR16859-20μg

Catalog No.: PR16859

Specification: 20ug/100ug/500ug/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:PD-L1 regulates immune responses by binding to the immunoinhibitory receptor PD-1 on activated T-cells and B-cells. This interaction can suppress T-cell responses by inducing apoptosis and arresting cell-cycle progression. In cancer, PD-L1's role in reducing antigen-specific T cells can promote tumor growth and immune evasion. As a result, PD-L1 is considered as a potential therapeutic target for autoimmune diseases and cancer.

Product Overview

Catalog No.
PR16859
SKU
PR16859-20μg
Category
Others Family
Product Type
Other
Size
20ug/100ug/500ug/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
CD274/PD-L1/B7-H1
Background
PD-L1 regulates immune responses by binding to the immunoinhibitory receptor PD-1 on activated T-cells and B-cells. This interaction can suppress T-cell responses by inducing apoptosis and arresting cell-cycle progression. In cancer, PD-L1's role in reducing antigen-specific T cells can promote tumor growth and immune evasion. As a result, PD-L1 is considered as a potential therapeutic target for autoimmune diseases and cancer.
Species
Canine
Source
HEK293 Cells
Tags
C-6His
Accession
NP_001278901.1
KnownAs
CD274, B7-H1
Protein Length
Phe19-Arg236
Predicted Molecular Mass
26 kDa
N-terminal Sequence
--
SDS-PAGE
35-45 kDa, reducing condition
Endotoxin
<0.1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>90% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3-6 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL, and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Others Family