Recombinant Canine CD152/CTLA4 protein, C-His

Recombinant Canine CD152/CTLA4 protein, C-His
Recombinant Canine CD152/CTLA4 protein, C-His
$290.00
Size:20μg
SKU: PR16860-20μg

Catalog No.: PR16860

Specification: 20ug/100ug/500ug/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:CTLA-4 is a protein belonging to the immunoglobulin superfamily and the CD28 receptor family. It interacts with CD80 (B7-1) and CD86 (B7-2) to transmit inhibitory signals to T cells, in contrast to CD28, which sends stimulatory signals. This receptor is also found within regulatory T cells, where it plays a vital role in their functions. CTLA-4 is a key regulator of T cell activation, making it an appealing candidate for autoimmune disease therapy and cancer immunotherapy. Recent evidence further highlights its importance in the function and balance of regulatory T cells (Treg).

Product Overview

Catalog No.
PR16860
SKU
PR16860-20μg
Category
Others Family
Product Type
Other
Size
20ug/100ug/500ug/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
CD152/CTLA4
Background
CTLA-4 is a protein belonging to the immunoglobulin superfamily and the CD28 receptor family. It interacts with CD80 (B7-1) and CD86 (B7-2) to transmit inhibitory signals to T cells, in contrast to CD28, which sends stimulatory signals. This receptor is also found within regulatory T cells, where it plays a vital role in their functions. CTLA-4 is a key regulator of T cell activation, making it an appealing candidate for autoimmune disease therapy and cancer immunotherapy. Recent evidence further highlights its importance in the function and balance of regulatory T cells (Treg).
Species
Canine
Source
HEK293 Cells
Tags
C-6His
Accession
NP_001003106.1
KnownAs
CD152
Protein Length
Lys36-Asp161
Predicted Molecular Mass
14 kDa
N-terminal Sequence
--
SDS-PAGE
18-23 kDa, reducing condition
Endotoxin
<0.1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>90% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3-6 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL, and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Others Family