Recombinant Human Galectin-14/LGALS14 protein, N-His

Recombinant Human Galectin-14/LGALS14 protein, N-His
Recombinant Human Galectin-14/LGALS14 protein, N-His
$210.00
Size:20μg
SKU: PR16941-20μg

Catalog No.: PR16941

Specification: 20ug/100ug/500ug/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Galectin-14 (Gal-14) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-14 is like Galectin-13, which is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. The galectin-14 enhances trophoblast migration and invasion via promoting the expression of MMP-9 and N-cadherin in the Akt pathway. Furthermore, galectin-14 stimulates the production of IL-8 in non-activated T cells, which associate with angiogenesis at the maternal-fetal interface.

Product Overview

Catalog No.
PR16941
SKU
PR16941-20μg
Category
Galectin family
Product Type
Other
Size
20ug/100ug/500ug/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
Galectin-14/LGALS14
Background
Galectin-14 (Gal-14) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-14 is like Galectin-13, which is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. The galectin-14 enhances trophoblast migration and invasion via promoting the expression of MMP-9 and N-cadherin in the Akt pathway. Furthermore, galectin-14 stimulates the production of IL-8 in non-activated T cells, which associate with angiogenesis at the maternal-fetal interface.
Species
Human
Source
E. coli
Tags
N-6His
Accession
Q8TCE9
KnownAs
LGALS14, CLC2, PPL13
Protein Length
Ser2-Asp139
Predicted Molecular Mass
16.9 kDa
N-terminal Sequence
--
SDS-PAGE
17 kDa, reducing condition
Endotoxin
<0.1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>98% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3-6 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL, and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Galectin family