Recombinant Human MTM1 protein, N-His

Recombinant Human MTM1 protein, N-His
Recombinant Human MTM1 protein, N-His
$290.00
Size:20μg
SKU: PR16951-20μg

Catalog No.: PR16951

Specification: 20ug/100ug/500ug/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:Myotubularin is a protein that plays a crucial role in cellular processes and is primarily associated with a rare genetic disorder called myotubular myopathy (MTM). This disorder primarily affects skeletal muscles and is characterized by severe muscle weakness and impaired motor function.

Myotubularin is an enzyme that regulates the levels of a lipid molecule called phosphatidylinositol 3-phosphate (PI3P) within cells. PI3P is involved in various cellular functions, including membrane trafficking and signaling pathways. Mutations in the gene encoding myotubularin lead to a deficiency or loss of its enzymatic activity, disrupting PI3P metabolism and causing the development of MTM.

Product Overview

Catalog No.
PR16951
SKU
PR16951-20μg
Category
Others Family
Product Type
Other
Size
20ug/100ug/500ug/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
MTM1
Background
Myotubularin is a protein that plays a crucial role in cellular processes and is primarily associated with a rare genetic disorder called myotubular myopathy (MTM). This disorder primarily affects skeletal muscles and is characterized by severe muscle weakness and impaired motor function. Myotubularin is an enzyme that regulates the levels of a lipid molecule called phosphatidylinositol 3-phosphate (PI3P) within cells. PI3P is involved in various cellular functions, including membrane trafficking and signaling pathways. Mutations in the gene encoding myotubularin lead to a deficiency or loss of its enzymatic activity, disrupting PI3P metabolism and causing the development of MTM.
Species
Human
Source
E. coli
Tags
N-6His
Accession
Q13496
KnownAs
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, CG2
Protein Length
Met1-Phe603
Predicted Molecular Mass
70.75 kDa
N-terminal Sequence
--
SDS-PAGE
60 kDa , reducing condition
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
>95% as determined by SDS-PAGE.
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3-6 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL, and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Contact Support

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Keywords:Others Family