- PackSize
- 50ug/100ug
- Target
- CD166
- Reactivity
- Human
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Humanized
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- Activated leukocyte cell adhesion molecule, MEMD, CD166 antigen, ALCAM, CD166
- Species
- --
- Gene ID-1
- Q13740
- Uniprot
- --
- Background
- Praluzatamab is a monoclonal antibody targeting the activated leukocyte cell adhesion molecule (ALCAM/CD116). Praluzatamab can be used to synthesize Praluzatamab ravtansine (antibody-drug conjugates). Praluzatamab can be used for research of cancers.<br>• Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activity., PMID:16204050<br/>• Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients., PMID:26134500<br/>• Predictive impact of activated leukocyte cell adhesion molecule (ALCAM/CD166) in breast cancer., PMID:18172759<br/>• Functional polymorphisms in CD166/ALCAM gene associated with increased risk for breast cancer in a Chinese population., PMID:21293922<br/>• Identification of clinically significant tumor antigens by selecting phage antibody library on tumor cells in situ using laser capture microdissection., PMID:16982673<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --