- PackSize
- 50ug/100ug
- Target
- shiga toxin type 1stx1B
- Reactivity
- Escherichia coli
- Applications
- ELISA, Bioactivity: FACS, Functional assay, Research in vivo
- Host Species
- Chimeric
- Isotype
- IgG1-kappa
- Conjugate/Modification
- --
- Recommended Dilution Ratio
- --
- Composition
- 0.01M PBS, pH 7.4.
- Purification Process
- Protein A/G purified from cell culture supernatant.
- Purity
- >95% purity as determined by SDS-PAGE.
- storageCondition
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
- Clonality
- Monoclonal
- Clone Number
- --
- Immunogen
- Mammalian Cells
- Alias
- shiga toxin type 1stx1B
- Species
- --
- Gene ID-1
- Q47641
- Uniprot
- --
- Background
- Pritoxaximab is an IgG1κ antibody targeting shiga toxin type 1.<br>• Shiga Toxin (Stx) Classification, Structure, and Function., PMID:25530917<br/>• Shiga-toxin-converting bacteriophages., PMID:11686382<br/>• <i>Escherichia albertii</i> Pathogenesis., PMID:32588811<br/>• Shiga Toxin-Producing <i>Escherichia coli</i> Infections during Pregnancy., PMID:30360505<br/>• Switching Shiga Toxin (Stx) Type from Stx2d to Stx2a but Not Stx2c Alters Virulence of Stx-Producing <i>Escherichia coli</i> (STEC) Strain B2F1 in Streptomycin (Str)-Treated Mice., PMID:33467588<br/>• Targeting bacterial toxins., PMID:22441768<br/>• Shiga toxin-induced haemolytic uraemic syndrome and the role of antibiotics: a global overview., PMID:31150744<br/>• L-Arabinose inhibits Shiga toxin type 2-converting bacteriophage induction in <i>Escherichia coli</i> O157:H7., PMID:37332116<br/>• Shiga toxin 2a and Enteroaggregative Escherichia coli--a deadly combination., PMID:26039753<br/>• Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model., PMID:36977098<br/>
- Tissue Expression
- --
- Signaling_pathway
- --
- Research Areas
- --