U-Blot® AQP2 (phospho Ser256) Polyclonal Antibody

Name: U-Blot® AQP2 (phospho Ser256) Polyclonal Antibody
SKU: WP10009
Availability: InStock

$288.00

Size:50μL

SKU: WP10009-50

Catalog No.: WP10009

Specification: 50μL/100μL

Stock: In stock

U-Blot® AQP2 (phospho Ser256) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008],

Product Overview

Catalog No.: WP10009
SKU: WP10009-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: AQP2
Reactivity: Human,Mouse,Rat
Application: IHC,IF,ELISA
MW(Calculated): 29kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Aquaporin 2 around the phosphorylation site of Ser256. AA range:222-271
Sequence: --
Specificity: Phospho-AQP2 (S256) Polyclonal Antibody detects endogenous levels of AQP2 protein only when phosphorylated at S256.
Gene Name: AQP2
Protein Name: Aquaporin-2
Other Name: AQP2;Aquaporin-2;AQP-2;ADH water channel;Aquaporin-CD;AQP-CD;Collecting duct water channel protein;WCH-CD;Water channel protein for renal collecting duct
Organism-1: Human
Gene ID-1: 359
SwissProt-1: P41181
Organism-2: Mouse
Gene ID-2: 11827
SwissProt-2: P56402
Organism-3: Rat
Gene ID-3: 25386
SwissProt-3: P34080
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Apical cell membrane ; Multi-pass membrane protein . Basolateral cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Shuttles from vesicles to the apical membrane (PubMed:15509592). Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane (PubMed:15509592). PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated (By similarity). .