U-Blot® IFN-α/βRα (phospho Tyr466) Polyclonal Antibody

Name: U-Blot® IFN-α/βRα (phospho Tyr466) Polyclonal Antibody
SKU: WP10020
Availability: InStock

$288.00

Size:50μL

SKU: WP10020-50

Catalog No.: WP10020

Specification: 50μL/100μL

Stock: In stock

U-Blot® IFN-α/βRα (phospho Tyr466) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP10020
SKU: WP10020-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IFN-α/βRα
Reactivity: Human,Rat,Mouse,
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 63kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human Interferon-alpha/beta Receptor alpha around the phosphorylation site of Tyr466. AA range:436-485
Sequence: --
Specificity: Phospho-IFN-α/βRα (Y466) Polyclonal Antibody detects endogenous levels of IFN-α/βRα protein only when phosphorylated at Y466.
Gene Name: IFNAR1
Protein Name: Interferon alpha/beta receptor 1
Other Name: IFNAR1;IFNAR;Interferon alpha/beta receptor 1;IFN-R-1;IFN-alpha/beta receptor 1;Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;CRF2-1;Type I interferon receptor 1
Organism-1: Human
Gene ID-1: 3454
SwissProt-1: P17181
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P33896
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Late endosome . Lysosome . Interferon binding triggers internalization of the receptor from the cell membrane into endosomes and then into lysosomes. .