U-Blot® HDAC8 (phospho Ser39) Polyclonal Antibody

Name: U-Blot® HDAC8 (phospho Ser39) Polyclonal Antibody
SKU: WP9160
Availability: InStock

$288.00

Size:50μL

SKU: WP9160-50

Catalog No.: WP9160

Specification: 50μL/100μL

Stock: In stock

U-Blot® HDAC8 (phospho Ser39) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Product Overview

Catalog No.: WP9160
SKU: WP9160-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HDAC8
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): 42kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39. AA range:5-54
Sequence: --
Specificity: Phospho-HDAC8 (S39) Polyclonal Antibody detects endogenous levels of HDAC8 protein only when phosphorylated at S39.
Gene Name: HDAC8
Protein Name: Histone deacetylase 8
Other Name: HDAC8;HDACL1;CDA07;Histone deacetylase 8;HD8
Organism-1: Human
Gene ID-1: 55869
SwissProt-1: Q9BY41
Organism-2: Mouse
Gene ID-2: 70315
SwissProt-2: Q8VH37
Organism-3: Rat
Gene ID-3: 100911968
SwissProt-3: B1WC68
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome . Cytoplasm . Excluded from the nucleoli (PubMed:10748112). Found in the cytoplasm of cells showing smooth muscle differentiation (PubMed:15772115, PubMed:16538051). .