U-Blot® IGF-IR (phospho Tyr1165/Y1166) Polyclonal Antibody

Name: U-Blot® IGF-IR (phospho Tyr1165/Y1166) Polyclonal Antibody
SKU: WP9172
Availability: InStock

$288.00

Size:50μL

SKU: WP9172-50

Catalog No.: WP9172

Specification: 50μL/100μL

Stock: In stock

U-Blot® IGF-IR (phospho Tyr1165/Y1166) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

Product Overview

Catalog No.: WP9172
SKU: WP9172-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IGF-1R
Reactivity: Human,Mouse,Rat,Monkey
Application: WB,ELISA
MW(Calculated): --
MW(Observed): pro:155kD,recetor beta:95kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180
Sequence: --
Specificity: Phospho-IGF-IR (Y1165/Y1166) Polyclonal Antibody detects endogenous levels of IGF-IR protein only when phosphorylated at Y1165/Y1166.
Gene Name: IGF1R
Protein Name: Insulin-like growth factor 1 receptor
Other Name: IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221
Organism-1: Human
Gene ID-1: 3480
SwissProt-1: P08069
Organism-2: Mouse
Gene ID-2: 16001
SwissProt-2: Q60751
Organism-3: Rat
Gene ID-3: 25718
SwissProt-3: P24062
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Single-pass type I membrane protein .