U-Blot® SGK1 (phospho Ser78) Polyclonal Antibody

Name: U-Blot® SGK1 (phospho Ser78) Polyclonal Antibody
SKU: WP9366
Availability: InStock

$288.00

Size:50μL

SKU: WP9366-50

Catalog No.: WP9366

Specification: 50μL/100μL

Stock: In stock

U-Blot® SGK1 (phospho Ser78) Polyclonal Antibody Learn more

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Background：This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009],

Product Overview

Catalog No.: WP9366
SKU: WP9366-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SGK1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA,IHC
MW(Calculated): --
MW(Observed): 54kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human SGK around the phosphorylation site of Ser78. AA range:41-90
Sequence: --
Specificity: Phospho-SGK1 (S78) Polyclonal Antibody detects endogenous levels of SGK1 protein only when phosphorylated at S78.
Gene Name: SGK1
Protein Name: Serine/threonine-protein kinase Sgk1
Other Name: SGK1;SGK;Serine/threonine-protein kinase Sgk1;Serum/glucocorticoid-regulated kinase 1
Organism-1: Human
Gene ID-1: 6446
SwissProt-1: O00141
Organism-2: Mouse
Gene ID-2: 20393
SwissProt-2: Q9WVC6
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q06226
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Cell membrane. Mitochondrion. The subcellular localization is controlled by the cell cycle, as well as by exposure to specific hormones and environmental stress stimuli. In proliferating cells, it shuttles between the nucleus and cytoplasm in synchrony with the cell cycle, and in serum/growth factor-stimulated cells it resides in the nucleus. In contrast, after exposure to environmental stress or treatment with glucocorticoids, it is detected in the cytoplasm and with certain stress conditions is associated with the mitochondria. In osmoregulation through the epithelial sodium channel, it can be localized to the cytoplasmic surface of the cell membrane. Nuclear, upon phosphorylation.; [Isoform 2]: Cell membrane.