U-Blot® GRK 2 (phospho Ser685) Polyclonal Antibody

Name: U-Blot® GRK 2 (phospho Ser685) Polyclonal Antibody
SKU: WP9489
Availability: InStock

$288.00

Size:50μL

SKU: WP9489-50

Catalog No.: WP9489

Specification: 50μL/100μL

Stock: In stock

U-Blot® GRK 2 (phospho Ser685) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP9489
SKU: WP9489-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GRK 2
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 80kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GRK2 around the phosphorylation site of Ser685. AA range:640-689
Sequence: --
Specificity: Phospho-GRK 2 (S685) Polyclonal Antibody detects endogenous levels of GRK 2 protein only when phosphorylated at S685.
Gene Name: ADRBK1
Protein Name: Beta-adrenergic receptor kinase 1
Other Name: ADRBK1;BARK;BARK1;GRK2;Beta-adrenergic receptor kinase 1;Beta-ARK-1;G-protein coupled receptor kinase 2
Organism-1: Human
Gene ID-1: 156
SwissProt-1: P25098
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q99MK8
Organism-3: Rat
Gene ID-3: 25238
SwissProt-3: P26817
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell membrane . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .