U-Blot® Rac GAP1 (phospho Ser387) Polyclonal Antibody

Name: U-Blot® Rac GAP1 (phospho Ser387) Polyclonal Antibody
SKU: WP9964
Availability: InStock

$288.00

Size:50μL

SKU: WP9964-50

Catalog No.: WP9964

Specification: 50μL/100μL

Stock: In stock

U-Blot® Rac GAP1 (phospho Ser387) Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016],

Product Overview

Catalog No.: WP9964
SKU: WP9964-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Rac GAP1
Reactivity: Human,Mouse,Rat,Monkey
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 72kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Ser387. AA range:353-402
Sequence: --
Specificity: Phospho-Rac GAP1 (S387) Polyclonal Antibody detects endogenous levels of Rac GAP1 protein only when phosphorylated at S387.
Gene Name: RACGAP1
Protein Name: Rac GTPase-activating protein 1
Other Name: RACGAP1;KIAA1478;MGCRACGAP;Rac GTPase-activating protein 1;Male germ cell RacGap;MgcRacGAP;Protein CYK4 homolg;CYK4;HsCYK-4
Organism-1: Human
Gene ID-1: 29127
SwissProt-1: Q9H0H5
Organism-2: Mouse
Gene ID-2: 26934
SwissProt-2: Q9WVM1
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm. Cytoplasm, cytoskeleton, spindle . Cytoplasmic vesicle, secretory vesicle, acrosome. Cleavage furrow. Midbody, Midbody ring . Cell membrane; Peripheral membrane protein; Cytoplasmic side. Colocalizes with RND2 in Golgi-derived proacrosomal vesicles and the acrosome (By similarity). During interphase, localized to the nucleus and cytoplasm along with microtubules, in anaphase, is redistributed to the central spindle and, in telophase and cytokinesis, to the midbody ring, also called Flemming body. Colocalizes with RHOA at the myosin contractile ring during cytokinesis. Colocalizes with ECT2 to the mitotic spindles during anaphase/metaphase, the cleavage furrow during telophase and at the midbody at the end of cytokinesis. Colocalizes with Cdc42 to spindle microtubules from prometaphase to telophase. .