U-Blot® PERK (Phospho Thr980) Rabbit mAb

U-Blot® PERK (Phospho Thr980) Rabbit mAb
U-Blot® PERK (Phospho Thr980) Rabbit mAb
$288.00
Size:50μL
SKU: WR4598-50

Catalog No.: WR4598

Specification: 50μL/100μL

Stock: In stock

U-Blot® PERK (Phospho Thr980) Rabbit mAb Learn more

Product information

Background:The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.
WR4598
SKU
WR4598-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
PERK
Reactivity
Mouse,Rat
Application
WB,IF,ELISA
MW(Calculated)
125kD
MW(Observed)
125kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
--
Clone No.
PT0868R
Immunogen
--
Sequence
--
Specificity
PERK (Phospho Thr980) Antibody detects endogenous levels of PERK protein only when phosphorylated at T980.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):YArHT
Gene Name
EIF2AK3
Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
Other Name
EIF2AK3;PEK;PERK;Eukaryotic translation initiation factor 2-alpha kinase 3;PRKR-like endoplasmic reticulum kinase;Pancreatic eIF2-alpha kinase;HsPEK
Organism-1
Human
Gene ID-1
9451
SwissProt-1
Q9NZJ5
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
Q9Z2B5
Organism-3
Rat
Gene ID-3
29702
SwissProt-3
Q9Z1Z1
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs