U-Blot® eIF2α (Phospho Ser51) Rabbit mAb

U-Blot® eIF2α (Phospho Ser51) Rabbit mAb
U-Blot® eIF2α (Phospho Ser51) Rabbit mAb
$288.00
Size:50μL
SKU: WR4667-50

Catalog No.: WR4667

Specification: 50μL/100μL

Stock: In stock

U-Blot® eIF2α (Phospho Ser51) Rabbit mAb Learn more

1
Share:fx@link

Product information

Product detailsSpecificationsQ & AEducation

Background：The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],

Product Overview

Catalog No.
WR4667
SKU
WR4667-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
eIF2α Phospho Ser51
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,ELISA
MW(Calculated)
36kD
MW(Observed)
36kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
IHC 1:100-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
--
Clone No.
PT0904R
Immunogen
--
Sequence
--
Specificity
eIF2α (Phospho Ser51) Monoclonal Antibody detects endogenous levels of eIF2α protein only when phosphorylated at S51.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ELsRR
Gene Name
EIF2S1
Protein Name
Eukaryotic translation initiation factor 2 subunit 1
Other Name
EIF2S1;EIF2A;Eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit alpha;eIF-2-alpha;eIF-2A;eIF-2alpha
Organism-1
Human
Gene ID-1
1965
SwissProt-1
P05198
Organism-2
Mouse
Gene ID-2
13665
SwissProt-2
Q6ZWX6
Organism-3
Rat
Gene ID-3
54318
SwissProt-3
P68101
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm, Stress granule . Colocalizes with NANOS3 in the stress granules. .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

WeChat / IMUcallm-Tech

HoursMonday-Friday 09:00-18:00 CST

Request Technical Support
Keywords:Rabbit mAbs