Sku: WR8148
U-Blot® p70 S6 Kinase (Phospho Thr389) Rabbit mAb
Catalog No.: WR4681
Specification: 50μL/100μL
Stock: In stock
U-Blot® p70 S6 Kinase (Phospho Thr389) Rabbit mAb Learn more
Product information
Background:ribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],
Product Overview
- Catalog No.
- WR4681
- SKU
- WR4681-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- p70 S6 kinase α
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IF,ELISA
- MW(Calculated)
- 59kD
- MW(Observed)
- 70kD
- Host Species
- Rabbit
- Isotype
- IgG, Kappa
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- --
- Clone No.
- PT0721R
- Immunogen
- --
- Sequence
- --
- Specificity
- p70 S6 Kinase (Phospho Thr389) Monoclonal Antibody detects endogenous levels of Phospho Atm around the phosphorylation site of Thr389 protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GFtYV
- Gene Name
- RPS6KB1 STK14A P70S6K
- Protein Name
- Ribosomal protein S6 kinase beta-1,p70 S6 Kinase (Thr389)
- Other Name
- RPS6KB1;STK14A;Ribosomal protein S6 kinase beta-1;S6K-beta-1;S6K1;70 kDa ribosomal protein S6 kinase 1;P70S6K1;p70-S6K 1;Ribosomal protein S6 kinase I;Serine/threonine-protein kinase 14A;p70 ribosomal S6 kinase alpha;p70 S6 kinas
- Organism-1
- Human
- Gene ID-1
- 6198
- SwissProt-1
- P23443
- Organism-2
- Mouse
- Gene ID-2
- 72508
- SwissProt-2
- Q8BSK8
- Organism-3
- Rat
- Gene ID-3
- 83840
- SwissProt-3
- P67999
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.; [Isoform Alpha I]: Nucleus. Cytoplasm.; [Isoform Alpha II]: Cytoplasm.
Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
Contact Support
Emailinfo@ucallmlabs.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
