U-Blot® Cofilin (Phospho Ser3) Rabbit mAb

U-Blot® Cofilin (Phospho Ser3) Rabbit mAb
U-Blot® Cofilin (Phospho Ser3) Rabbit mAb
$288.00
Size:50μL
SKU: WR4788-50

Catalog No.: WR4788

Specification: 50μL/100μL

Stock: In stock

U-Blot® Cofilin (Phospho Ser3) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],

Product Overview

Catalog No.
WR4788
SKU
WR4788-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Cofilin Phospho Ser3
Reactivity
Human,Mouse,Rat
Application
WB,IF,ELISA
MW(Calculated)
19kD
MW(Observed)
25kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
Ser3
Recommended Dilution Ratio
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0749R
Immunogen
--
Sequence
--
Specificity
Cofilin (Phospho Ser3) Antibody detects endogenous levels of Cofilin protein only when phosphorylated at S3.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MAsGV
Gene Name
CFL1
Protein Name
Cofilin-1
Other Name
CFL1;CFL;Cofilin-1;18 kDa phosphoprotein;p18;Cofilin;non-muscle isoform
Organism-1
Human
Gene ID-1
3716
SwissProt-1
P23528
Organism-2
Mouse
Gene ID-2
12631
SwissProt-2
P18760
Organism-3
Rat
Gene ID-3
29271
SwissProt-3
P45592
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Nucleus matrix . Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, lamellipodium membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, lamellipodium . Cell projection, growth cone . Cell projection, axon . Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs