U-Blot® Synuclein-α (Phospho Ser129) Rabbit mAb

U-Blot® Synuclein-α (Phospho Ser129) Rabbit mAb
U-Blot® Synuclein-α (Phospho Ser129) Rabbit mAb
$288.00
Size:50μL
SKU: WR4840-50

Catalog No.: WR4840

Specification: 50μL/100μL

Stock: In stock

U-Blot® Synuclein-α (Phospho Ser129) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016],

Product Overview

Catalog No.
WR4840
SKU
WR4840-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Synuclein-α
Reactivity
Human,Mouse,Rat
Application
WB,IF,IP,ELISA
MW(Calculated)
14kD
MW(Observed)
18kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
Ser129
Recommended Dilution Ratio
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1002R
Immunogen
--
Sequence
--
Specificity
Synuclein-α (Phospho Ser129) Antibody detects endogenous levels of Synuclein-α protein only when phosphorylated at S129.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MPsEE
Gene Name
SNCA
Protein Name
Alpha-synuclein
Other Name
SNCA;NACP;PARK1;Alpha-synuclein;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor;NACP
Organism-1
Human
Gene ID-1
6622
SwissProt-1
P37840
Organism-2
Mouse
Gene ID-2
20617
SwissProt-2
O55042
Organism-3
Rat
Gene ID-3
29219
SwissProt-3
P37377
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Membrane . Nucleus . Cell junction, synapse . Secreted . Cell projection, axon . Membrane-bound in dopaminergic neurons (PubMed:15282274). Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (By similarity). .

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs