U-Blot® Endothelin A Receptor Rabbit mAb

U-Blot® Endothelin A Receptor Rabbit mAb
U-Blot® Endothelin A Receptor Rabbit mAb
$268.00
Size:50μL
SKU: WR4978-50

Catalog No.: WR4978

Specification: 50μL/100μL

Stock: In stock

U-Blot® Endothelin A Receptor Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

Product Overview

Catalog No.
WR4978
SKU
WR4978-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
ETAR
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,ELISA
MW(Calculated)
49kD
MW(Observed)
65kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Thr18/Ser19
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1210R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
EDNRA
Protein Name
Endothelin-1 receptor
Other Name
EDNRA;ETA;ETRA;Endothelin-1 receptor;Endothelin A receptor;ET-A;ETA-R;hET-AR
Organism-1
Human
Gene ID-1
1909
SwissProt-1
P25101
Organism-2
Mouse
Gene ID-2
13617
SwissProt-2
Q61614
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Function:Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with HDAC7 and HTATIP.,tissue specificity:Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.,

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

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Keywords:Rabbit mAbs