U-Blot® HMGCR Rabbit mAb

Name: U-Blot® HMGCR Rabbit mAb
SKU: WR5072
Availability: InStock

$268.00

Size:50μL

SKU: WR5072-50

Catalog No.: WR5072

Specification: 50μL/100μL

Stock: In stock

U-Blot® HMGCR Rabbit mAb Learn more

U-Blot® HMGCR Rabbit mAb

Target: HMGCR
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,IP,ELISA
MW(Calculated): 98kD
MW(Observed): 98kD
Host Species: Rabbit
Isotype: IgG,Kappa
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: Protein A
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: PT1309R
Immunogen: --
Sequence: --
Specificity: Endogenous
Gene Name: HMGCR
Protein Name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)
Other Name: --
Organism-1: Human
Gene ID-1: 3156
SwissProt-1: P04035
Organism-2: Mouse
Gene ID-2: 15357
SwissProt-2: Q01237
Organism-3: Rat
Gene ID-3: 25675
SwissProt-3: P51639
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis . HMGCR is the main target of statins, a class of cholesterol-lowering drugs .

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Keywords:Rabbit mAbs