U-Blot® AMPKα1 (Phospho Ser485) Rabbit mAb

U-Blot® AMPKα1 (Phospho Ser485) Rabbit mAb
U-Blot® AMPKα1 (Phospho Ser485) Rabbit mAb
$288.00
Size:50μL
SKU: WR5145-50

Catalog No.: WR5145

Specification: 50μL/100μL

Stock: In stock

U-Blot® AMPKα1 (Phospho Ser485) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WR5145
SKU
WR5145-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
AMPKα1
Reactivity
Human,Mouse,Rat
Application
WB,IF,ELISA
MW(Calculated)
62kD
MW(Observed)
62kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Ser51
Modification site
Phospho
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1374R
Immunogen
--
Sequence
--
Specificity
AMPKα1 (Phospho Ser485) Antibody detects endogenous levels of AMPKα1 protein only when phosphorylated at S485.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):EAkSG
Gene Name
PRKAA1 AMPK1
Protein Name
AMPKα1 (Ser485)
Other Name
5'-AMP-activated protein kinase catalytic subunit alpha-1;AMPK subunit alpha-1;Acetyl-CoA carboxylase kinase;ACACA kinase;Hydroxymethylglutaryl-CoA reductase kinase;HMGCR kinase;Tau-protein kinase PRKAA1;
Organism-1
Human
Gene ID-1
5562
SwissProt-1
Q13131
Organism-2
Mouse
Gene ID-2
105787
SwissProt-2
Q5EG47
Organism-3
Rat
Gene ID-3
65248
SwissProt-3
P54645
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Nucleus . In response to stress, recruited by p53/TP53 to specific promoters. .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs