U-Blot® p57kip2 Rabbit mAb

Background：P57kip2 is a cell cycle inhibitor and tumor suppressor. The gene is mainly located on the mother's chromosome 11. By blocking the G1 / S phase transition in the cell cycle , we can realize the negative regulation of the cell cycle , and then prevent cell proliferation and tumor formation. In complete hydatidiform mole , there is a lack of maternal gene and p57 negative expression , while in partial hydatidiform mole , there are genes of both parents and p57 positive expression , which can be used for the study of early hydatidiform mole pregnancy.