U-Blot® Pan-Itaconyl-Cysteine Rabbit pAb

Catalog No.: WT9030
Specification: 100μL/300μL
Stock: In stock
Product details, specifications, documents, and related products are available from the catalog record. Learn more
Product information
Background:Itaconyl-Cysteine (C(itacon)) is a novel metabolism-dependent post-translational modification occurring on cysteine residues of proteins. This modification is mediated by itaconate, a metabolite abundantly produced under immune activation and inflammatory conditions, via covalent reaction with the thiol group of cysteine. Itaconylation is widely involved in key biological processes including inflammatory signaling, oxidative stress response, innate immunity, and metabolic reprogramming. It plays critical regulatory roles in the development of inflammatory diseases, infectious immunity, and metabolism-related disorders, serving as an important molecular marker and research target linking immunometabolism and protein function regulation.
Product Overview
- Catalog No.
- WT9030
- SKU
- WT9030-100
- Category
- Itaconate-Mediated Modifications
- Product Type
- Other
- Size
- 100μL/300μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- Store at -20°C. Avoid repeated freeze-thaw cycles
- Research Use Only
- Yes
Additional Specifications
- Antibody Type
- Polyclonal
- Target
- Itaconyl-Cysteine
- Reactivity
- Species Independent
- Application
- WB,IHC-P,ICC/IF,FC
- MW(Calculated)
- Multiple
- MW(Observed)
- Multiple
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate
- Unconjugated
- Modification
- Cysteine itaconylation
- Modification Site
- Cys(C)
- Recommended dilution ratio
- WB 1:1000;IHC-P 1:100-1:200;ICC/IF 1:100-1:200;FC 1:100-1:200
- Composition
- PBS, Glycerol, BSA,NaN3
- Purification process
- Protein A
- storageCondition
- Store at -20°C. Avoid repeated freeze-thaw cycles
- Stability
- Stable for 12 months from date of receipt / reconstitution.
- Concentration
- --
- Clonal
- Polyclonal
- Clone Number
- --
- Immunogen
- polypeptide
- Gene Name
- --
- Protein Name
- --
- Alternative name
- CIta
- Organism-1
- --
- Gene ID
- --
- SwissProt-1
- --
- --
- Background:
- Background
- Itaconyl-Cysteine (C(itacon)) is a novel metabolism-dependent post-translational modification occurring on cysteine residues of proteins. This modification is mediated by itaconate, a metabolite abundantly produced under immune activation and inflammatory conditions, via covalent reaction with the thiol group of cysteine. Itaconylation is widely involved in key biological processes including inflammatory signaling, oxidative stress response, innate immunity, and metabolic reprogramming. It plays critical regulatory roles in the development of inflammatory diseases, infectious immunity, and metabolism-related disorders, serving as an important molecular marker and research target linking immunometabolism and protein function regulation.
- Cellular Localization
- --
- --
- Background:Itaconyl-Cysteine (C(itacon)) is a novel metabolism-dependent post-translational modification occurring on cysteine residues of proteins. This modification is mediated by itaconate, a metabolite abundantly produced under immune activation and inflammatory conditions, via covalent reaction with the thiol group of cysteine. Itaconylation is widely involved in key biological processes including inflammatory signaling, oxidative stress response, innate immunity, and metabolic reprogramming. It plays critical regulatory roles in the development of inflammatory diseases, infectious immunity, and metabolism-related disorders, serving as an important molecular marker and research target linking immunometabolism and protein function regulation.
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Tech Support
ucallm
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
Storage & Handling
- Storage
- Store at -20°C. Avoid repeated freeze-thaw cycles
Contact Support
Emailinfo@mail.ucallm.com
Phone+(1)-866-986-9598
WeChat / IMUcallm-Tech
HoursMonday-Friday 09:00-18:00 CST
