Benzoylation

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Introduction

Lysine benzoylation (Kbz) is a reversible aromatic lysine acylation modification. Using benzoyl‑CoA as its acyl donor, this marker accumulates mainly on histone tails within gene promoters to remodel chromatin and mediate transcriptional regulation.

Products Solutions

We provide antibody‑based detection and enrichment tools for lysine benzoylation analysis, including a MultiPTM Rabbit Monoclonal Antibody mix designed for improved recognition of Kbz‑modified proteins.

  • Multiple antibody formats
  • Multi‑epitope antibody composition
  • Kbz motif enrichment

Product List

Product TypeProduct NameCatalog No.
Rabbit pAbPanBenzoyllysine Rabbit pAbWT9036
Rabbit mAbPanBenzoyllysine Rabbit mAbWT9037
Mouse mAbPanBenzoyllysine Mouse mAbWT9175
MultiPTMBenzoyllysine MultiPTM Rabbit Monoclonal Antibody mixWT9037M
Motif(BenzoylK) KitBenzoylLysine Motif (BenzoylK) KitWT919K

Research Areas

  • Epigenetic regulation

References

  1. Huang H, Zhang D, Wang Y, et al. Lysine benzoylation is a histone mark regulated by SIRT2. Nat Commun. 2018;9(1):3374. Published 2018 Aug 28.
  2. Li T, Chen J, Mi K, et al. Probiotics derived sodium benzoate improves social behavior of offspring exposed in the maternal immune activation through regulation of histone lysine benzoylation in astrocytes. Mol Psychiatry. 2025;30(12):5849‑5864.
  3. Wang D, Yan F, Wu P, et al. Global profiling of regulatory elements in the histone benzoylation pathway. Nat Commun. 2022;13(1):1369.

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