Protein Carbonylation

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Introduction

Protein carbonylation is an irreversible oxidative modification characterized by the formation of carbonyl groups on proteins. It can arise directly from amino acid oxidation or indirectly through reactions with reactive carbonyl species generated during oxidative stress. Protein carbonylation is widely studied as an indicator of oxidative protein damage and cellular redox imbalance.

Products Solutions

Our human protein oxidation antibody arrays combine carbonyl labeling with antibody‑based multiplex detection, enabling high‑throughput profiling of carbonylated proteins across hundreds to thousands of predefined targets. Multiple array formats are available for different screening scale and research needs.

  • High‑throughput protein carbonylation profiling
  • Multiplex detection of carbonylated proteins
  • Broad protein target coverage
  • Multiple array formats

Research Areas

  • Aging
  • Neurodegenerative Diseases
  • Cardiovascular Diseases

References

  1. Chaubey K, Vázquez‑Rosa E, Tripathi SJ, et al. Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain. Cell Rep Med. 2026;7(1):102535.
  2. Koutakis P, Hernandez H, Miserlis D, et al. Oxidative damage in the gastrocnemius predicts long‑term survival in patients with peripheral artery disease. NPJ Aging. 2024;10(1):21.

 

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