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NK Cell Activation

Natural killer (NK) cells are important cytotoxic lymphocytes of the innate immune system, and their activation mechanisms differ from those of T cells and B cells.

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Primary Immune Cells

Primary immune cells are immune cells directly isolated from human or animal tissues, including peripheral blood mononuclear cells (PBMCs), T cells, B cells, NK cells, monocytes, macrophages, and dendritic cells.

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Macrophage Activation

Macrophages are important innate immune effector cells whose functions are highly dependent on the surrounding tissue microenvironment and stimulation signals.

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B Cell Activation

B cells primarily recognize antigens through the B-cell receptor (BCR) and initiate intracellular signaling cascades.

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T Cell Activation

T-cell activation is a central process in adaptive immune responses.

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Origin and Differentiation of Immune Cells

Hematopoietic stem cells (HSCs) are the fundamental cellular source responsible for the generation and maintenance of immune cells.

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Myeloid Immune Cells

Myeloid immune cells encompass macrophages, DCs and granulocytes. They drive innate immune responses, execute pathogen elimination, inflammation and tissue homeostasis.

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Lymphoid Immune Cells

Lymphoid immune cells including T, B and NK cells bridge innate and adaptive immunity, mediating pathogen clearance, anti‑tumor defense and immune homeostasis.

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Overview of Immune Cells

Immune cells are essential functional cells that maintain immune defense and immune homeostasis in the body. They play central roles in infection defense, inflammation regulation, tumor immunity, tissue repair, and the study of immune-related diseases.

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