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Showing content associated with PTMs.
TopicItaconate-Mediated Modifications
Itaconate is an immunometabolite that drives two distinct protein modifications: cysteine itaconation (S-itaconation) and lysine itaconylation (K-itaconylation).
TopicProtein Carbonylation
Protein carbonylation is an irreversible oxidative modification characterized by the formation of carbonyl groups on proteins.
TopicProtein Citrullination
Protein citrullination is an irreversible PTM that converts arginine residues to citrulline through peptidyl arginine deiminases (PADs).
TopicS-Nitrosylation
S-Nitrosylation involves the reversible attachment of nitric oxide (NO) to cysteine thiols, forming S-nitrosothiols (SNOs).
TopicCarboxyethylation
Carboxyethylation includes two distinct types of protein modifications with different mechanisms and biological functions.
TopicSerotonylation
Serotonylation is a recently characterized PTM, wherein serotonin is covalently conjugated to glutamine residues of substrate proteins.
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