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Application SolutionsProtein‑protein interaction-LCA (Luciferase Complementation Assay)
Luciferase Complementation Assay (LCA) is a highly sensitive, high-throughput protein-protein interaction detection technology based on the principle of protein fragment complementation.
Application SolutionsProtein‑protein interaction-Y2H (Yeast two-hybrid)
Yeast Two-Hybrid (Y2H) is an in vivo protein-protein interaction screening technology based on the modular structure of transcription factors.
Application SolutionsProtein‑protein interaction-Co-IP (Co-Immunoprecipitation)
Co-IP is a classical in vivo protein-protein interaction technology developed based on the principle of Immunoprecipitation (IP).
Application SolutionsProtein‑protein interaction-Pull‑down
The pull-down assay is an effective in vitro technique for validating protein-protein interactions, commonly used to confirm interacting proteins identified by yeast two-hybrid systems or other screening methods.
Application SolutionsProtein Carbonylation
Protein carbonylation is an irreversible oxidative modification characterized by the formation of carbonyl groups on proteins.
Application SolutionsProtein Citrullination
Protein citrullination is an irreversible PTM that converts arginine residues to citrulline through peptidyl arginine deiminases (PADs).
Application SolutionsS-Nitrosylation
S-Nitrosylation involves the reversible attachment of nitric oxide (NO) to cysteine thiols, forming S-nitrosothiols (SNOs).
Application SolutionsTyrosine Nitration (3-Nitrotyrosine)
Protein tyrosine nitration is a non-enzymatic PTM triggered by reactive nitrogen species (RNS) under oxidative and inflammatory conditions.
Application SolutionsCarboxyethylation
Carboxyethylation includes two distinct types of protein modifications with different mechanisms and biological functions.
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